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Table 1.11.  Trends in Duke’s response to therapy.

  VetBooks.ir  Time    (bpm)  (% / g/dL)  (mmol/L)  Assessment        Therapy
                       Heart
                       rate
                                        Lactate
                               PCV/TP
             (minutes)
              0       190–200  45/6.0     5.4   Lateral recumbency, dull   Isotonic crystalloid bolus 22 mL/kg
                                                 mentation
              20       180       –        –     Lateral recumbency, dull   Isotonic crystalloid bolus 22 mL/kg
                                                 mentation
              35       168       –        –     Sternal recumbency, quiet    Colloid bolus 5 mL/kg
                                                 but responsive       Fentanyl bolus 3 μg/kg
              55       150     38/4.5     2.7   Sternal recumbency, alert    Continue isotonic crystalloid
                                                 and responsive         120 mL/kg/day
                                                                      Fentanyl CRI for pain
                                                                        (3 μg/kg/h)
              70       140       –        –     Sternal recumbency, alert    Continue isotonic crystalloid
                                                 and responsive,        120 mL/kg/day
                                                Exhibiting pain       Fentanyl CRI for pain
              95       165     34/3.0     3.5   Sternal recumbency, but   Repeat abdominal fast scan
                                                 quieter than previous,   confirmed hemoabdomen, apply
                                                 abdomen noted to be    abdominal compression wrap,
                                                 distended              continue isotonic crystalloid
                                                                        120 mL/kg/day, fentanyl CRI,
                                                                        colloid bolus 2.5μmL/kg
              120      155       –        –     Sternal recumbency,    Isotonic crystalloid 120 mL/kg/
                                                 continues to be quiet but   day, maintain abdominal wrap,
                                                 responsive, abdomen no   fentanyl CRI
                                                 change               Antibiotics started (open fracture)
              140      146     34/3.0     3.0   Sternal recumbency, quiet    Isotonic crystalloid 120 mL/kg/
                                                 but responsive, abdomen    day, maintain abdominal wrap,
                                                 no change              fentanyl CRI
              160      138     30/3.0     2.5   Sternal recumbency, quiet   Isotonic crystalloid rate decreased
                                                but responsive, abdomen no   to 90 mL/kg/day, maintain
                                                 change                 abdominal wrap, fentanyl CRI
              215      135       –        –     Sternal recumbency, but will   Isotonic crystalloid rate decreased to
                                                 change positions, more   90 mL/kg/day, loosen abdominal
                                                 alert responsive, engaged,   wrap, fentanyl CRI
                                                 abdomen no change
              270      130     32/2.8     2.2   Sternal recumbency, but will   Fluid rate decreased to 90 mL/
                                                 change positions, more   kg/day, fentanyl CRI, maintain
                                                 alert responsive, engaged,   loosened abdominal wrap
                                                 abdomen no change
             CRI, constant-rate infusion.


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