Page 45 - Basic Monitoring in Canine and Feline Emergency Patients
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Table 2.2.  Conditions known to be associated with    stroke volume and blood pressure (Fig. 2.3).
             secondary hypertension in dogs and cats.    Animals with cardiogenic shock experience
  VetBooks.ir  Associated conditions  Examples           decreased forward flow from the left ventricle and
                                                         also have a decreased stroke volume/blood pressure
                                                         (Fig. 2.3), while patients in hypovolemic shock
              Kidney disease
                                 Chronic kidney disease
                                 Acute kidney injury     have a decreased circulating blood volume which,
                                 Glomerular disease      when sufficiently diminished, leads to a decreased
              Endocrinopathy     Diabetes mellitus       venous return to the heart (preload) and a subse-
                                 Hyperadrenocorticism    quent drop in stroke volume and blood pressure
                                  (dogs)                 (Fig. 2.3). Animals suffering from septic shock fre-
                                 Hyperthyroidism (cats)  quently exhibit multiple forms of shock as their
              Neoplasia          Primary hyperaldosteronism  illness likely leads to some measure of hypovolemia
                                 Pheochromocytoma        while the systemic inflammatory response may eas-
              Drugs              Glucocorticoids         ily have a depressive effect on both cardiac function
                                 Mineralocorticoids      (inotropy) and maintenance of vascular tone.
                                 Phenylpropanolamine       Anesthesia can also be associated with hypoten-
                                 Toceranib phosphate     sion for numerous reasons,  necessitating  blood
                                 Erythropoiesis-stimulating   pressure monitoring. Many anesthetic drugs cause
                                  agents                 cardiopulmonary depression (decreased heart rate
                                 Ephedrine/pseudoephedrine  or  inotropy)  or affect  vasomotor  tone  leading  to
              Miscellaneous      Obesity                 decreased SVR (Fig. 2.3). Positive pressure ventila-
                                 Brachycephalic airway   tion during anesthesia may lead to decreased
                                  disease (dogs)         venous return to the heart by compressing the vena
                                                         cava or other components of the venous system, in
                                                         turn decreasing preload and negatively affecting
             also have a blood pressure measurement performed.   stroke volume (Fig. 2.3). Hypoxemia during anes-
             Furthermore, some drugs (e.g. phenylpropanolamine)   thesia can deplete energy reserves and lead to
             are known to cause hypertension. Patients receiving   peripheral vasodilation as individual tissues make
             such drugs should have their blood pressure routinely   efforts to preserve oxygen delivery. At a local level,
             monitored before starting and while taking the medi-  such responses to tissue hypoxia are advantageous;
             cation. Dogs or cats receiving medication aimed at   however,  if  tissue  hypoxia  is  more  global,  wide-
             lowering blood pressure should also have their blood   spread peripheral vasodilation can contribute to
             pressure monitored after starting therapy.  hypotension. Moreover, hypercapnia occurring
                                                         under anesthesia causes global smooth muscle
                                                         relaxation as a direct effect of carbon dioxide on
             Hypotension
                                                         the smooth muscle of the vasculature. For many of
             Hypotension usually occurs in more critically ill   these reasons, mild hypotension is frequently noted
             animals. Patients suffering from various forms of   even in healthy animals undergoing anesthesia, and
             shock are at risk for hypotension and warrant   unhealthy animals are even more likely to display
             blood pressure monitoring. Major presentations of   hypotension.
             shock include hypovolemic shock (e.g. marked
             blood loss either through external hemorrhage or   2.4  Interpretation of the Findings
             internal/cavitary hemorrhage), distributive shock
             (e.g. anaphylaxis  with diffuse  vasodilation),   A blood pressure measurement may be interpreted
             obstructive shock (e.g. gastric dilatation-volvulus   as either elevated (hypertension), normal, or low
             placing pressure on the vena cava and occluding   (hypotension).
             the venous blood supply), cardiogenic shock (e.g.
             dilated cardiomyopathy leading to markedly
             reduced forward blood flow from the left ventri-  Hypertension
             cle), and septic shock. Animals with obstructive or   When considering the potentially hypertensive
             distributive shock have a diminished venous return   patient, a reading <140 mmHg is generally considered
             to  the  heart, which  in  turn  leads  to  a decreased   to be normal. The vast majority (>80%) of hypertensive


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