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the autonomic nervous system. Stimuli that increase   3.2  The Monitor: How Does
            sympathetic nervous system (SNS) activity (causing   an ECG Machine Work?
  VetBooks.ir  increased  β1-adrenergic stimulation to the heart)   The ideal way to measure cardiac conduction is to
            will increase the rate of SA node depolarization and
                                                         place catheters inside the heart that can measure
            AV  nodal conduction (see  Table 3.2). In contrast,
            stimuli that increase parasympathetic nervous sys-  electrical activation at each point within the heart.
            tem (PNS) activity (causing increased vagal stimu-  Obviously, this is not practical in most settings.
            lation  to the  heart)  will  decrease  the  rate  of  SA   Instead, metal electrodes are placed on the outside
            node depolarization and AV nodal conduction (see   of the body to measure electric potentials moving
            Table 3.2). The two arms of the autonomic nervous   between them.  The pattern of electric potentials
            system thus have a major influence on heart rate   measured on the body surface can be used to infer
            and occurrence of certain ECG abnormalities dis-  how electricity  is moving  through  the heart. For
            cussed in this chapter.                      example, if electricity is measured moving from an
                                                         electrode placed on the right forelimb to an elec-
                                                         trode on the left forelimb, then one can infer that
                                                         the electricity moved from right to left within the
                                                         heart.
                SA node                                   An ECG  lead is created by placing two elec-
                                                         trodes on opposite  ‘sides’ of the heart in some
                                                         configuration (for example, on the right and
               AV node                                   left  forelimbs, or on the left forelimb and left
                         RA          LA
                                                         hindlimb).  The ECG machine arbitrarily labels
                                                         one electrode in the pair as the ‘positive’ electrode
               Bundle                                    and one as the ‘negative’ electrode. When the ECG
               of His                                    detects electricity moving  towards the positive
                                                         electrode,  the  machine  creates  a  positive  deflec-
                            RV        LV
               Bundle                                    tion on the screen or paper for that lead. When the
               branches                                  ECG  detects electricity  moving  away  from  the
                                                         positive electrode (towards the negative elec-
                                                         trode), the machine creates a  negative deflection
                                                         on the screen or paper for that lead. Finally, if
                     Purkinje
                     fibers                              electricity is moving exactly perpendicular to the
                                                         two electrodes, no deflection is recorded for that
                                                         lead (termed isoelectric).
                                                          Having multiple leads allows the ECG to ‘look’
            Fig. 3.1.  Schematic depiction of the cardiac conduction
            system. See text for details. RA, right atrium; RV, right   at electricity moving through the heart from dif-
            ventricle; LA, left atrium; LV, left ventricle; SA, sinoatrial;   ferent angles.  The most common electrode and
            AV, atrioventricular.                        lead configuration involves three electrodes

            Table 3.1.  Events in cardiac conduction as depicted on an ECG.
            Depolarization of this structure       Causes this waveform on an ECG
             Sinoatrial node                       Before P wave
             Atria                                 P wave
             Atrioventricular node                 PR interval
             His bundle / bundle branches          PR interval
             Ventricles                            QRS complex
                                                   Q = first negative deflection
                                                   R = first positive deflection
                                                   S = first negative deflection after R wave
             Ventricular repolarization            T wave



             46                                                                           J.L. Ward
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