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Aflatoxins Chapter | 69  993




  VetBooks.ir  naturally occurring carcinogen. AFs target the liver, the  Chaytor, A.C., See, M.T., Hansen, J.A., et al., 2011. Effects of chronic
                                                                  exposure of diets with reduced concentrations of aflatoxin and deox-
             immune system, reproduction, and have teratogenic and
                                                                  ynivalenol on growth and immune status of pigs. J. Anim. Sci. 89,
             epigenetic effects. The differences between species in the
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                                                                Clark, J.D., Mahaffey, E.A., Hatch, R.C., et al., 1980. Experimentally induced
             differences in toxicity. The reaction of AFB 1 epoxide
                                                                  chronic aflatoxicosis in rabbits. Am. J. Vet. Res. 41, 1841 1845.
             with DNA, RNA, and proteins are important mechanisms
                                                                Cook, W.O., Richard, J.L., Osweiler, G.D., et al., 1986. Clinical and
             of intoxication. Agronomic practices, pest control, and
                                                                  pathologic changes in acute bovine aflatoxicosis: rumen motility and
             ensuring that stored commodities cannot support growth
                                                                  tissue and fluid concentrations of aflatoxins B 1 and M 1 . Am. J. Vet.
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             test for exposure. The interactions of mycotoxins are  Coppock, R.W., Jacobsen, B.J., 2009. Mycotoxins in animal and human
             important considerations in terms of predicting safe expo-  patients. Toxicol. Ind. Health. 25, 637 655.
             sure of humans and animals to mycotoxins.          Coppock, R.W., Reynolds, R.D., Buck, W.B., et al., 1989. Acute aflatox-
                                                                  icosis in feeder pigs, resulting from improper storage of corn. J. Am.
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