Page 1065 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

Ergot and Fescue Toxicoses Chapter | 70 997

VetBooks.ir N O

HO H
O N
C
H 3
CH 3
H C OH O NH
3
O O
N
O NH H
N
H O
H
O N
CH 3
N H
CH 3
H
N
H
HN
Ergocristine Ergotamine

CH 3
H C OH OH
3
3
O H C
N O N
O NH H H
N O NH
H O H N O
H
O CH 3 O H
H C CH 3
3
N N
CH 3 CH 3 CH 3
H H
Ergosine Ergocornine
HN HN
CH 3
H C OH O NH
3
O
N OH
O NH H
N
H O CH 3
H
O
CH 3
N
N CH 3
CH 3
CH 3 H
H
HN Ergocryptine HN Ergonovine
FIGURE 70.2 Chemical structures of some ergot alkaloids.

concentrations in dairy and beef cows consuming endo- 2004b, 2012). Effects of ergovaline and other ergot
phyte infected fescue as well as diminished feed intake alkaloids on other reproductive hormones include low
associated with ingestion of endophyte infected fescue progesterone production in both cows and mares, dimin-
can be reflected by decreased milk production (up to ished progestagens in late-gestational mares, suppressed
50%) observed after the perinatal period (Evans et al., relaxin associated with possible impaired placental