Page 1437 - Small Animal Internal Medicine, 6th Edition

CHAPTER 88 Lymphadenopathy and Splenomegaly 1409

TABLE 88.1
VetBooks.ir Classification of Lymphadenopathies in Dogs and Cats TYPE SPECIES

SPECIES
TYPE
Proliferative and Inflammatory Lymphadenopathies Viral
Infectious Canine viral enteritides D
Feline immunodeficiency virus C
Bacterial
Actinomyces spp. D, C Feline infectious peritonitis C
Borrelia burgdorferi D Feline leukemia virus C
Brucella canis D Infectious canine hepatitis D
Corynebacterium spp. C Noninfectious
Mycobacterium spp. D, C Dermatopathic lymphadenopathy D, C
Nocardia spp. D, C
Streptococci D, C Drug reactions D, C
Contagious streptococcal lymphadenopathy C Idiopathic D, C
Yersinia pestis C Distinctive peripheral lymph node hyperplasia C
Bartonella spp. D, C Plexiform vascularization of lymph nodes C
Localized bacterial infection D, C Immune-mediated disorders
Septicemia D, C Systemic lupus erythematosus D, C
Rickettsial Rheumatoid arthritis D
Ehrlichiosis D, C Immune-mediated polyarthritides D, C
Anaplasmosis D, C “Puppy strangles” (juvenile cellulitis) D
RMSF D Other immune-mediated disorders D, C
Salmon poisoning D Localized inflammation D, C
Fungal Postvaccinal D, C
Aspergillosis D, C
Blastomycosis D, C Infiltrative Lymphadenopathies
Coccidioidomycosis D Neoplastic
Cryptococcosis D, C Primary hemolymphatic neoplasms
Histoplasmosis D, C Leukemias D, C
Phaeohyphomycosis D, C Lymphomas D, C
Phycomycosis D, C Malignant histiocytosis D, C
Sporotrichosis D, C Multiple myeloma D, C
Pneumocystis spp. D Systemic mast cell disease D, C
Other mycoses D, C Metastatic neoplasms
Algal Carcinoma D, C
Protothecosis D, C Malignant melanoma D
Parasitic Mast cell tumor D, C
Babesiosis D Sarcoma D, C
Cytauxzoonosis C
Demodicosis D, C Nonneoplastic
Hepatozoonosis D Eosinophilic granuloma complex C, D
Leishmaniasis D Mast cell infiltration (nonneoplastic) D, C
Neospora caninum D
Toxoplasmosis D, C
Trypanosomiasis D

C, Cats; D, dogs; RMSF, Rocky Mountain spotted fever.
Modified from Hammer AS, et al.: Lymphadenopathy. In Fenner NR, editor: Quick reference to veterinary medicine, ed 2, Philadelphia,
1991, JB Lippincott.

When evaluating dogs and cats with lymphadenopathy or and Flat Coated retrievers; others have a defined geographic
diffuse splenomegaly, the clinician can glean important or seasonal prevalence, including leishmaniasis in the Medi-
information from the history. Certain diseases are prevalent terranean region of Europe, salmon poisoning in the Pacific
in certain breeds, such as mycobacterial infections in Basset Northwest, and some systemic mycoses, such as histoplas-
Hounds and Schnauzers; histiocytic neoplasms in Bernese mosis in the Ohio River Valley. Systemic (constitutional)
Mountain dogs, Rottweilers, Labradors, Golden Retrievers, clinical signs are usually present in dogs with systemic