Page 924 - Small Animal Internal Medicine, 6th Edition

896 PART VI Endocrine Disorders

VetBooks.ir Drugs Used in Endocrine Disorders RECOMMENDED DOSAGE

GENERIC NAME (TRADE
NAME) PURPOSE DOG CAT

Calcium—injectable and oral Treat hypocalcemia, Treat See Box 53.7 See Box 53.7
preps hypoparathyroidism
Carbimazole Treat feline NA 2.5-5 mg PO q12h initially;
(Neo-Mercazole) hyperthyroidism increase q2wk to effect
Chlorpropamide (Diabinase) Treat partial central 5-20 mg/kg PO q12h Unknown
diabetes insipidus
Chlorothiazide (Diuril) Treat central/renal 20-40 mg/kg PO q12h 20-40 mg/kg PO q12h
diabetes insipidus
Desmopressin (DDAVP) Treat central diabetes 1-4 drops of nasal spray in 1-4 drops of nasal spray in
insipidus conjunctival sac q12-24h; conjunctival sac q12-24h;
tablets: 0.05-0.2 mg/dog tablets: 0.05 mg/cat PO
PO q8-12h q8-12h
Desoxycorticosterone pivalate Treat hypoadrenocorticism 2.2 mg/kg, IM or SC, q25d 2.2 mg/kg, IM or SC, q25d
(DOCP) initially initially
Dexamethasone sodium Treat acute addisonian 0.5-1 mg/kg IV, repeat 0.5-1 mg/kg IV, repeat q12h
phosphate crisis q12h at 0.05-0.1 mg/kg at 0.05-0.1 mg/kg in IV
in IV fluids fluids
Diazoxide (Proglycem) Treat hypoglycemia 5 mg/kg PO q12h initially Unknown
caused by β-cell
neoplasia
Fludrocortisone acetate Treat hypoadrenocorticism 0.01 mg/kg PO q12h 0.05-0.1 mg/cat PO
(Florinef) initially
Glucagon USP Treat hypoglycemia 5-10 ng/kg/min as Unknown
caused by a β-cell continuous IV infusion;
neoplasia adjust dose to effect
Growth hormone—porcine Treat pituitary dwarfism 0.1 IU/kg SC 3 times/wk Unknown
origin for 4-6 weeks
Insulin Treat diabetic ketoacidosis See Box 49.11 See Box 49.11
Treat diabetes mellitus See Table 49.3 See Table 49.3
Provide supportive See Table 53.3 See Table 53.3
treatment for
hyperkalemia
Ketoconazole (Nizoral Treat 5 mg/kg PO q12h initially, Not recommended
hyperadrenocorticism increase to effect q2wk
Melatonin Treat alopecia X 3 mg (dogs ≤ 15 kg) or NA
syndrome 6 mg (dogs >15 kg) PO
q12h for 6-8 weeks
initially
Methimazole (Felimazole) Treat hyperthyroidism 2.5 mg/dog PO q12h 2.5 mg/cat PO q12h initially;
initially; increase q2wk to increase q2wk to effect
effect
o,p′DDD (Mitotane, Lysodren) Treat canine Induction: 25 mg/kg PO Not recommended
hyperadrenocorticism q12h until controlled
Long-term treatment of Maintenance: 25-50 mg/kg
hypoadrenocorticism PO per week initially
divided into 2 or 3 doses
Phenoxybenzamine Supportive treatment 0.5 mg/kg PO q12h Unknown
(Dibenzyline) forpheochromocytoma initially, gradually increase
to effect