Page 1048 - Veterinary Immunology, 10th Edition

VetBooks.ir Type II Hypersensitivity in Infectious

Diseases

Just as drugs can be adsorbed onto red cells and render them
immunologically foreign, so too can bacterial antigens such as the
lipopolysaccharides, viruses such as equine infectious anemia virus
and Aleutian disease virus, bacteria such as Anaplasma, and

protozoa such as the trypanosomes and Babesia. These altered red
cells are regarded as foreign and are either lysed by antibody and
complement or phagocytosed by mononuclear phagocytes.
Clinically severe anemia is therefore characteristic of all these

infections.

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