Page 1055 - Veterinary Immunology, 10th Edition

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FIG. 32.1 The mechanisms of an Arthus reaction as well as a
histological section of an Arthus reaction in the skin of a cat 6 hours
after intradermal inoculation of chicken red blood cells. (Courtesy Dr. A.
Kier.)

The fate of the injected antigen can be followed if it is labeled
with a fluorescent dye. The antigen first diffuses from the injection
site through tissue fluid. When small blood vessels are encountered,
the antigen diffuses into the vessel walls, where it encounters

circulating antibodies. Immune complexes form and are deposited

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