Page 376 - Veterinary Immunology, 10th Edition

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FIG. 13.8 Major surface receptors of T cells, their ligands, and
their functions.

CD molecules on the cells of the domestic mammal fall into two

categories. Most are also expressed on human and mouse cells
(homologs) and thus have the same CD number. There are,
however, several cell surface molecules in domestic mammals that
have no recognized homolog in human or mouse. These

unattributable molecules are given a species abbreviation and the
prefix WC (workshop cluster); for example, BoWC1 and BoWC2 are
found in cattle. Many of these WC molecules have subsequently
been shown to be homologous to previously recognized CD

molecules. The phenotypes of cells as expressed by their cell surface
molecules are characterized through the use of an instrument called
a flow cytometer. This is described in Chapter 42.

Antigen Receptor Complexes

While lymphocytes express thousands of proteins on their surface,

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