Page 835 - Veterinary Immunology, 10th Edition

to the appropriate licensing authorities as well as to the vaccine
VetBooks.ir manufacturer. Because MLV vaccines carry with them the risks for

residual virulence and for contamination with other agents, certain
countries will not approve their use.

Inactivated vaccines are commonly available in liquid form and
usually contain suspended adjuvant. These should not be frozen,
and they should be shaken well before use. The presence of
preservatives such as phenol or merthiolate will not control

massive bacterial contamination, and multidose containers should
be discarded after partial use. Many vaccines containing MLV are
susceptible to heat inactivation but are much more resistant if
lyophilized. Remember, however, that intense sunlight and heat

can destroy even lyophilized vaccines. They store well but should
be kept cool and away from light and should only be reconstituted
with the fluid provided by the manufacturer.

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