Page 849 - Veterinary Immunology, 10th Edition

and a lack of cellular immune responses. Thus sheep with PB
VetBooks.ir lesions mount a type 1 response, whereas those with MB disease

mount a type 2 response.

FIG. 26.3 The two forms of Johne's disease in sheep. A, Section
of terminal ileum from a case of multibacillary Johne's disease,
showing abundant acid-fast organisms within large infiltrating
macrophages. B, Section of terminal ileum from a case of
paucibacillary Johne's disease, showing very few acid-fast bacteria
and a significant lymphocyte infiltration. Ziehl-Nielsen stain. (Courtesy
Dr. C.J. Clarke.)

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