Page 153 - Problem-Based Feline Medicine
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9 – THE CAT WITH ABNORMAL HEART SOUNDS AND/OR AN ENLARGED HEART  145


           It is important to note that due to the thickness of  If the patient is in congestive heart failure, refer to
           the septum in a normal heart, many times there is  hypertrophic cardiomyopathy section (page 130) for
           the illusion of an echo drop out. Multiple views must  treatment details.
           be obtained to reach a diagnosis.
           Doppler confirmation of left-to-right shunting is doc-  Prognosis
           umented across the atrial septal defect.
                                                          Prognosis is good in most cases, but it depends on the
           Doppler study may show variable degrees of mitral  degree of shunt fraction, which is dependent on the degree
           regurgitation.                                 of mitral regurgitation present.
           Relative pulmonic stenosis (blood flow velocity > 2.0  Many cats have a normal lifespan.
           m/s) secondary to increased volume of blood may be
           seen with significant shunt fractions.
           In severe cases, biatrial and bi-ventricular enlargement  MITRAL VALVE DYSPLASIA/STENOSIS
           can be seen.
                                                           Classical signs
           Cardiac catheterization
                                                           ● Systolic and/or diastolic murmur is heard
           A catheter can be passed across the interatrial sep-  over the left apex.
           tum into the left atria and ventricle.          ● Dyspnea.
           An increase greater than 5% in oxygen saturation at the  ● Thromboembolic disease
           level of the right atrium when compared with blood
           from the caudal vena cava is indicative of an atrial sep-  Pathogenesis
           tal defect with left-to-right shunting.
                                                          Congenital mitral valve malformation will result in poor
           Angiographic contrast study from the left atria will
                                                          coaptation of its leaflets and secondary regurgitation.
           show shunting of blood into the right heart with opaci-
           fication of the right atria and ventricle.     In some cases, the mitral valve is thick and misshapen
                                                          with restricted motility during diastole, causing impaired
           Differential diagnosis                         blood flow from the left atrium to the left ventricle.
           Cardiomyopathy is uncommon in young cats.      In some cases, more than two leaflets may be present.
           Cardiomyopathy murmurs are usually not as loud.  Most commonly, the anterior leaflet may be subdivided
           Cardiomyopathy murmurs may sound different with  and it is called a cleft mitral valve.
           serial auscultations.
                                                          Clinical signs
           Ventricular septal defects usually have a louder murmur
           on the right sternal border and the character is harsher.  A heart murmur is heard loudest over the left heart apex
                                                          and is present from a young age.
           Mitral valve dysplasia occurs with a murmur louder at
           the apex, in some cases a diastolic murmur may be pres-  Dyspnea or respiratory distress occur if congestive
           ent if there is significant mitral stenosis.   heart failure is present.
           Pulmonic or aortic stenosis present with louder and  Signs of increased respiratory rate, dyspnea or col-
           harsher murmurs than atrial septal defects.    lapse may be seen while playing.

                                                          Lameness, paralysis or paresis may result from sys-
           Treatment
                                                          temic thromboembolism.
           Many cases are asymptomatic and there is no need for
                                                          Atrial arrhythmias may be present if there is severe left
           therapy.
                                                          atrial enlargement. Atrial premature contractions,
           Definitive therapy requires surgical repair, which is  paroxysmal atrial tachycardia or atrial fibrillation can
           very difficult to accomplish in veterinary medicine.  be seen.
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