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148  PART 3   CAT WITH SIGNS OF HEART DISEASE


          Prognosis                                     The murmur is best heard at the left heart base. It is an
                                                        ejection systolic murmur, which varies in intensity dur-
          Prognosis is dependent on severity of the stenosis and
                                                        ing systole because of the crescendo and decrescendo
          the presence of congestive heart failure with or without
                                                        character.
          collapse.
                                                        Characterization of the ejection murmur may be diffi-
          Some cats may have a normal lifespan.
                                                        cult in a cat because of the fast heart rate.
          Severely affected cats die within the first 1–2 years of life.
                                                        Diagnosis
          Cats with aortic stenosis are at an increased risk of
          developing bacterial valvular endocarditis.
                                                        Radiographic findings
                                                        Normal cardiac size or right ventricular enlargement is
          PULMONIC STENOSIS                             found.

                                                        Dilated main pulmonary artery (post-stenotic dilata-
           Classical signs
                                                        tion) is seen as a bulge in the left cranio-lateral part of
           ● Systolic murmur is heard over the left heart  the cardiac silhouette in the ventro-dorsal view or
             base over the pulmonic area.               dorso-ventral view.

                                                        Under-perfused pulmonary circulation is seen as
          Pathogenesis
                                                        hypovascular lung fields characterized by hyperinflated
          With congenital valvular malformation of the pulmonic  lungs and a decreased peripheral pulmonary vasculature.
          valve, there is  thickening of the valve leaflets and
                                                        Electrocardiographic findings
          poor motility during systole, resulting in fixed
                                                        Tachycardia is frequently seen with a heart rate greater
          obstruction of outflow of blood. In some cases,
                                                        than 220 bpm.
          supravalvular or subvalvular stenosis may be found.
                                                        Right axis deviation is seen between  −60 and  −180
          The increased resistance to blood flow across the pul-
                                                        degrees in the frontal plane.
          monary valve stenosis results in elevation of right ven-
          tricular systolic pressure. Secondary right ventricular  Deep S waves are seen on leads II, aVF and III.
          hypertrophy and dilation may develop, along with
          arrhythmias.                                  Echocardiographic findings
          Dilation and hypertrophy of the right ventricle may  Pulmonary valve stenosis is present. Pulmonary
          result in secondary tricuspid insufficiency.  artery hypoplasia and a dysplastic pulmonic valve
                                                        may be evident.
          Signs of right-sided congestive heart failure may develop.
                                                        Doppler study across the pulmonary valve will deter-
          Pulmonic stenosis is often seen with other cardiac
                                                        mine the degree of stenosis. Velocities of blood flow
          defects such as tetralogy of Fallot, septal defects and
                                                        obtained by continuous wave Doppler above 2.0 m/s are
          tricuspid dysplasia.
                                                        diagnostic of stenosis.
          It is a rare congenital defect in cats.
                                                        Cardiac catheterization findings
          Clinical signs                                Selective angiography of the right ventricle will show:
                                                         ● Right ventricular hypertrophy.
          Many cats are asymptomatic and present for evalua-
                                                         ● Pulmonary valve stenosis and post-stenotic dilata-
          tion of a heart murmur.
                                                           tion of the main pulmonary artery.
          The age of presentation varies from the  first few
          months of life until middle age.
                                                        Differential diagnosis
          Cats with symptoms may show dyspnea or open-mouth
          breathing after mild to moderate exercise.    Tetralogy of Fallot.
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