Page 198 - Problem-Based Feline Medicine
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190  PART 4   CAT WITH URINARY TRACT SIGNS


          Urethral rupture may result in subcutaneous accumu-  Clinical signs
          lation of urine in the perineal region leading to
                                                        Small amounts of urine are frequently voided while the
          swelling, discoloration and necrosis of the skin.
                                                        urinary bladder is still small.
          Clinical signs                                Dribbling urine (incontinence) associated with a small
                                                        bladder.
          Dysuria.
                                                        Pollakiuria.
          Stranguria.
                                                        Palpation of the bladder often initiates the act of
          Perineal swelling.
                                                        urination.
          Red discoloration of the perineal skin.

          Abdominal pain.                               *Diagnosis
          Signs of post-renal renal failure.            Diagnosis is based on clinical signs, especially that the
                                                        cat frequently urinates or  dribbles urine when the
          Diagnosis                                     bladder is quite small.

          History of trauma or catheterization.         Urodynamic procedures, such as cystometrography,
                                                        demonstrate reduced threshold volumes and pressure,
          Clinical signs of swelling, discoloration or necrosis in  which indicate reduced bladder compliance or
          the perineal region.                          detrussor hypercontractility.

          Positive-contrast urethrography will demonstrate  Urinalysis may reveal pyuria or neoplasia.
          extravasation of contrast into the periurethral soft tis-
          sue. If the rupture is at the proximal end of the urethra,  Radiography may help to determine the underlining
          contrast agent may enter the abdomen.         cause, for example neoplasia and cystitis (thickened
                                                        bladder wall).
                                                        FeLV test.
          HYPERCONTRACTILE BLADDER*

           Classical signs                              Differential diagnosis
           ● Small urinary bladder.                     Infectious cystitis/urethritis – hematuria, pyuria and
           ● Dribbling urine.                           bacteriuria are usually present.
           ● Pollakiuria.
                                                        Non-obstructed LUTD – hematuria is usually present.

          Pathogenesis
                                                        Treatment
          Hypercontractility of the urinary bladder occurs when
          detrusor muscle contractions are triggered at low  Management of storage dysfunction of the urinary
          volumes and pressure, resulting in dysfunction of uri-  bladder may include elimination of urinary tract
          nary bladder storage.                         inflammation, correction of neurologic disorders or
                                                        pharmacologic manipulation to reduce detrusor muscle
          It may be due to reduced bladder capacity (hypoplas-
                                                        excitability.
          tic bladder, neoplasia), excessive sensory input
                                                         ● Always treat urinary tract infections first before
          (inflammation) or neurologic disorders (upper motor
                                                           attempting pharmacologic manipulation.
          neuron lesions).
                                                         ● Parasympathetic inhibitors (anticholinergic
          Bladder hypercontractibility (idiopathic detrusor insta-  agents), such as  propantheline (5–7.5 mg /cat
          bility), not associated with any known cause, has been  orally every 72 hours or more frequently as
          reported in one cat with FeLV that responded to anti-  required) and oxybutynin (0.5–1.25 mg/cat orally
          cholinergic therapy.                             every 8–12 hours) may be used.
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