Page 208 - Problem-Based Feline Medicine
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200   PART 4   CAT WITH URINARY TRACT SIGNS


          Diagnosis                                     Clinical signs

          Diagnosis is via  radiography using retrograde ure-  Normal or small urinary bladder.
          thrography.
                                                        Intermittent leakage of small volumes of urine, often
          Following catheterization of the urethera using an  while the cat is sleeping or relaxed.
          open-ended cat catheter, contrast is injected (1–2 ml)
                                                        If congenital in origin, other anomalies, such as vaginal
          while the radiographs are taken. Avoid over-distending
                                                        aplasia and cystic hypoplasia are commonly present.
          the urinary bladder.
                                                        Many FeLV-positive cats with urinary incontinence
          Urodynamic procedures such as urethral pressure
                                                        may also have  anisocoria, reproductive disorders,
          profilometry may be used to identify focal urethral
                                                        weight loss, vomiting and ptyalism suggesting a multi-
          obstructions.
                                                        focal autonomic dysfunction. In cats with FeLV-asso-
                                                        ciated incontinence, digital palpation of the urinary
          Treatment                                     bladder often elicits a urine flow.
          Treatment depends on location and size of the stricture.  In cats with urethral incompetence due to neoplasia,
                                                        abdominal palpation may reveal a mass at the bladder
          Extrapelvic strictures may be managed by urethros-
                                                        neck. Others signs, such as dysuria and hematuria are
          tomy, whereas, intrapelvic strictures may require ure-
                                                        often present.
          thral resection and anastomosis.
                                                        Secondary urinary tract infections are common.
          URETHRAL INCOMPETENCE*
                                                        Diagnosis
           Classical signs
                                                        Diagnosis is based on history and clinical signs of leak-
           ● Small urinary bladder.
                                                        age of small amounts of urine, often when sleeping, and
           ● Intermittent dribbling of urine.
                                                        a normal or small bladder.
                                                        Ophthalmological signs (anisocoria) may suggest the
          Pathogenesis                                  incontinence is associated with FeLV infection.
          Incontinence occurs because of reduced urethral outflow  A positive FeLV test.
          resistance during urine storage. This results from lost or
                                                        Retrograde contrast vaginourethrography in female cats
          reduced urethral smooth or striated muscle tone.
                                                        with urethral hypoplasia shows marked urethral short-
          Reported causes of urethral incompetence include:  ening and other anomalies, such as vaginal aplasia and
          ● Pelvic and pudendal nerve damage following  cystic hypoplasia.
            trauma (cystotomy, perineal urethrostomy) and
                                                        Cystography or retrograde urethrography may reveal a
            rarely neoplasia (acquired urethral incompe-
                                                        mass at the bladder neck. Biopsy is necessary for a
            tence).
                                                        definitive diagnosis.
          ● Dysraphism in Manx cats.
          ● Urethral hypoplasia has been reported in young  Urodynamic procedures, including urethral pressure pro-
            female cats (congenital urethral incompetence).  filometry can be used to identify urethral incompetence.
          ● A relationship between incontinence and  feline
            leukemia virus (FeLV) infection is suspected.
          ● Reproductive hormone-responsive incontinence  Differential diagnosis
            has been reported in two female cats following  Hypercontractile bladder (urge incontinence) is charac-
            ovariectomy and suspected in three neutered  terized by frequent conscious urination and a small
            males.                                      bladder.
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