Page 211 - Problem-Based Feline Medicine
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12 – THE INCONTINENT CAT  203


                                                          Affected cats may voluntarily pass a small amount of
           EXSTROPHY
                                                          urine with difficulty.
            Classical signs                               Typically there is a large flaccid urinary bladder (detru-
                                                          sor atony), which is easily manually expressed.
            ● Urine dribbles from abdominal defect.
                                                          Other clinical signs usually predominate, such as an
                                                          acute onset over 24–48 h of depression and anorexia,
           Clinical signs                                 gastrointestinal signs (dysphagia, regurgitation, vomit-
                                                          ing, tenesmus, diarrhea, constipation), mydriasis, pro-
           Very rare disorder in cats characterized by ventral mid-
                                                          lapsed third eyelids, dry mucous membranes and
           line defects in the ventral abdominal wall, urinary blad-
                                                          bradycardia.
           der, intestines and external genitalia.
           Easily differentiated from other causes of incontinence
           as urine dribbles from the abdominal defect.
                                                          Diagnosis
           Diagnosis                                      Diagnosis is based on clinical examination findings of
                                                          a flaccid bladder associated with acute onset of depres-
           Diagnosis is based on clinical signs. Exstrophy should  sion and gastrointestinal and ocular signs.
           be differentiated from patent urachus.
                                                          Radiographic signs are of megesophagus and a dis-
                                                          tended urinary bladder.
           FELINE DYSAUTONOMIA
                                                          Ophthalmological examination reveals reduced tear
            Classical signs                               production, dilated poorly responsive pupils in a visual
                                                          cat, and prolapsed third eyelids.
            ● Dribbling urine.
            ● Distended bladder.                          Urodynamic procedures include the following:
            ● Gastrointestinal and ocular signs.          ● Cystometry and urethral pressure profilometry may
                                                             be used to objectively evaluate detrussor and ure-
                                                             thral function.
           Pathogenesis                                   ● Cystometrograms can be used to show large filling
                                                             volumes, and lack of a sustained contractile peak
           Feline dysautonomia is an autonomic polyganglionopa-  indicates detrussor atony.
           thy (Key–Gaskell syndrome).                    ● Urethral pressure profilometry can be used to iden-

           Autonomic ganglia (sympathetic and parasympathetic)  tify urethral incompetence.
           are affected resulting in detrusor atony and urethral
           sphincter incompetence.
           Overflow incontinence occurs as a result.      Treatment
                                                          Bethanecol is effective in inducing urination in some
                                                          cases, although it should not be used in cats with slow
           Clinical signs
                                                          resting heart rates, as profound bradycardia and cardiac
           Mainly seen in young cats.                     arrhythmia may occur.
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