Page 144 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition
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Basic laboratory diagnostics                                                                                                                                                                                Basic laboratory diagnostics
       Haematology                                                                                                                                                                                                             Haematology

       Rubrik                                                                                                                         Rubrik
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                                              Thrombocytosis                                                                                                               Thrombocytopenia






                                                                                                                                                                                  Increased                      Decreased
          Reduced storage                  Emptying of                              Increased                                             Sequestration       Destruction        consumption                     production
              space                         storage                                production




                                                                                                                                                           – Immune-           – DIC                                        Primarily
                                                                                                                                          Splenomegaly       mediated          – Haemorrhage         Pancytopenia        thrombocytic line
          Asplenia (e.g. after   Emptying of bone   Emptying of spleen   Uncontrolled        Stimulation                                                     thrombo-                                                       affected
            splenectomy)          marrow                                 production
                                                                                                                                                             cytopenia
                                                                                                                                                           – Anaplasmosis
                                                                                                                                                             (Anaplasma
                                                                                                                                         – Systemic          platys infection)                    – Lymphoma           – Ehrlichiosis and
                                                                      – Megakaryocyte      – Regenerative                                 infection                                               – Drug toxicity        other rickettsial
                                                   Glucocorticoid                                                                        – Autoimmune                                              (e.g. cytostatics,    infections
                              Vincristin therapy                        leukaemia (rare)    overproduction
                                                     influence                              (e.g. massive                                 disease                                                  sulphonamides)      – Oestrogen
                                                                                            regeneration of                              – Splenic                                                – Oestrogen            intoxication (dog)
                                                                                            erythrocytes or                               neoplasia                                                intoxication (dog)  – FeLV infection (cat)
                                                                                            neutrophils)                                 – Splenic torsion                                        – Chronic ehrlichiosis
                                                                                                                                                                                                  – Leishmaniosis
                                                 – Hyperadreno-                                                                                                                                   – Intoxication
                                                   corticism                                                                                                                                       (e.g. lead, thallium)
                                                 – Iatrogenic                                                                                                                                     – FeLV infection (cat)
                                                   (glucocorticoid
                                                   therapy)





































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