Page 150 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition
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Basic laboratory diagnostics                                                                                                                                                                                Basic laboratory diagnostics
       Haematology                                                                                                                                                                                                             Haematology

       Rubrik                                                                                                                         Rubrik
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                                                                                                                                                                                        Neutrophilia
                                            Neutropenia




                                                                                                                                                              Left shift
                       Left shift                                                                                                                            (increased                                        No left shift
                      (increased                                   No left shift                                                                             production)
                      production)

                                                                                                                                                                                                                           Adaption of bone
                                                                                                                                                                                                 Centralisation of            marrow to
                                                                                                                                                            Inflammation
                                 Increased       Marginalisation of                                                                                                                              neutrophil pool            chronic excess
                                                                                  Decreased
            Destruction        consumption         the neutrophil                 production                                                                                                                                 consumption
                             (demand > supply)        pool

                                                                                                                                                                                                 Malfunction of            – Chronic
                                                                                                                                          Autoimmune          Infection       Neoplasia         leukocyte adhesion
                                                                                                                                            disease                                                                          bacterial
             Immune-         – Pus                                                           Primarily                                                                                              protein                  infection
             mediated          accumulation           Shock           Pancytopenia       neutrophil cell lines                                                                                                             – Neoplasia
            neutropenia        (e.g. abscess,                                                affected
                               pyometra,                                                                                                – Immune-          – Systemic                                       Congenital
                               pyothorax)                                                                                                 mediated          bacterial                      Acquired        (rare, e.g. in
                             – Sepsis                                                                                                     haemolytic        infection                                       Irish Setter)
                                                                    – Lymphoma          – Recent damage                                   anaemia          – Hepato-
                                                                    – Drug toxicity       to the bone                                                       zoonosis
                                                                      (e.g. cytostatics,   marrow (e.g.                                                    – Parvovirus
                                                                      sulphonamides)      radiation,                                                        infection (in      Glucocorticoid
                                                                    – Oestrogen           therapy with                                                      recovery)            influence             Stress
                                                                      intoxication        chemotherapeutics)
                                                                      (dog)             – Parvovirus infection
                                                                    – Chronic
                                                                      ehrlichiosis                                                                                           – Hyperadreno-
                                                                    – Leishmaniosis                                                                                            corticism
                                                                    – Intoxication                                                                                           – Iatrogenic
                                                                      (e.g. lead,                                                                                              (glucocorticoid
                                                                      thallium)                                                                                                therapy)
                                                                    – FeLV infection
                                                                      (cat)






















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