Page 155 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition

Basic laboratory diagnostics

Serum enzyme activities
* Rubrik

VetBooks.ir

Increased ALT*

Muscle
cell damage Liver cell damage

– Myositis
(e.g. toxoplasmosis, Secondary to
lupus erythematosus) Primary liver disease
– Muscle trauma extrahepatic disease

– Hepatitis/Cholangitis – Sepsis
– FIP (cat) – Pancreatitis
– Lymphoma – Intestinal barrier
– Hepatocellular dysfunction
carcinoma – Hypothyroidism (dog)
– Hepatic lipidosis (cat) – Hyperthyroidism (cat)
– Drug toxicity – Diabetes mellitus
(e.g. NSAID, doxycycline) – Hyperadrenocorticism
– Toxins (e.g. aflatoxins) – Hypoxaemia
(e.g. cardiovascular
disorders, anaemia)

*

* Decreased ALT activity is not clinically relevant

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