Page 157 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition

Basic laboratory diagnostics

Serum enzyme activities
Rubrik

VetBooks.ir

Increased AST*

Muscle cell
Haemolysis Liver cell damage
damage

â True Secondary to
Pseudo- Skeletal muscle Cardiac muscle Primary liver
haemolysis haemolysis cell damage cell damage disease extrahepatic
p. 131 disease

– Trauma – Myocar- – Hepatitis/ – Sepsis
Prolonged – Myositis ditis Cholangitis – Pancreatitis
storage of whole – Muscle – Infarction – FIP (cat) – Intestinal
blood sample contractions – Lymphoma barrier
before (e.g. tetanus, – Hepatocellular dysfunction
centrifugation seizures) carcinoma – Hypothyroidism
– Hepatic lipidosis (dog)
(cat) – Hyperthyroidism
– Drug toxicity (cat)
(e.g. NSAIDs, – Diabetes
doxycycline) mellitus
– Toxin (e.g. – Hyperadreno-
aflatoxin) corticism
– Hypoxaemia
(e.g.
cardiovascular
disorders,
anaemia)

* Decreased AST activity is not clinically relevant

147