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125  Management of Chronic Kidney Disease  1173

               regarding the importance of monitoring and follow‐up   been associated with a poorer prognosis and should be
  VetBooks.ir  will improve compliance.                           targets for disease management to maximize survival.
                                                                  Typically, CKD progresses much more slowly in cats
                                                                  than in dogs. Dogs with stage 3 and 4 CKD quickly
                 Prognosis                                          progress and within months to a year or two may be
                                                                  euthanized due to the disease. Cats with early CKD can
               Predicting prognosis in CKD can be somewhat challeng-  have stable disease, typically for years, and may die of
               ing as the progression of disease varies substantially   another disease process. Cats with stage 3 and 4 typically
               between individuals. Poor body condition, proteinuria,     progress more slowly than dogs at a similar disease stage
               hypertension, hyperphosphatemia, and anemia have all   and may still live months to years.



                 Further Reading

               Brown S, Elliott J, Francey T, et al. Consensus    Foster JD. Update on mineral and bone disorders in
                 recommendations for standard therapy of glomerular   chronic kidney disease. Vet Clin North Am Small Anim
                 disease in dogs. J Vet Intern Med 2013; 27(Suppl 1):   Pract 2016; 46: 1131–49.
                 S27–43.                                          Quimby JM, Lunn KF. Mirtazapine as an appetite
               Cianciolo RE, Brown CA, Mohr FC, et al. Pathologic   stimulant and anti‐emetic in cats with chronic kidney
                 evaluation of canine renal biopsies: methods for   disease: a masked placebo‐controlled crossover clinical
                 identifying features that differentiate immune‐mediated   trial. Vet J 2013; 197: 651–5.
                 glomerulonephritides from other categories of    Sparkes AH, Caney SM, Chalhoub S, et al. ISFM consensus
                 glomerular diseases. J Vet Intern Med 2013; 27(Suppl 1):   guidelines on the diagnosis and management of feline
                 S10–18.                                            chronic kidney disease. J Feline Med Surg 2016; 18: 219–39.
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