Page 103 - Veterinary Immunology, 10th Edition
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FIG. 4.4 Activation of C3 involves its cleavage by C3 convertase.
This exposes a thioester bond between a cysteine and a glutamine.
This bond breaks to form a reactive carbonyl group that enables the
molecule to bind covalently (and hence irreversibly) to target cell
surfaces. Removal of C3a also reveals the binding sites for FH and
FB.
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