Page 200 - Veterinary Immunology, 10th Edition

other infectious diseases, injury, and cancer. α -acid glycoprotein
VetBooks.ir also increases in FIP, although this is usually less than 10-fold. It
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also increases in calicivirus, chlamydiosis, feline leukemia, and

feline immunodeficiency virus infections. Haptoglobin usually
increases 2- to 10-fold and is especially high in FIP.
In dogs, CRP is the major acute-phase protein, increasing 100-fold

in infectious diseases such as pyometra-associated sepsis,
babesiosis, leishmaniasis, parvovirus infection, and colibacillosis.
APP levels increase moderately in canine inflammatory bowel
disease. CRP, haptoglobin, and SAA are significantly elevated in
the cerebrospinal fluid and serum of dogs with canine steroid-

responsive arteritis-meningitis (Chapter 37). In pregnant dogs,
haptoglobin, ceruloplasmin, and fibrinogen levels increase midway
through gestation. SAA also increases in pyometra.

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