Page 22 - Veterinary Immunology, 10th Edition

dermatitis, type I diabetes mellitus, equine laminitis, and systemic
VetBooks.ir lupus are shown to be more complex than previously believed.

New advances in therapy are covered, including the introduction
of immune checkpoint therapy in cancer and the use of monoclonal

antibody therapy and intravenous immunoglobulin therapy for
immune-mediated diseases. The exciting new developments in the
use of nanoparticles in vaccines and as adjuvants are now
described. The significant roles of vitamins A and D as well as the

aryl hydrocarbon receptor in immunity are also recognized.
Advances in basic science that are now discussed include new
findings on the structure and genetics of bovine antibodies,
epigenetics, RNA interference, microRNA, macrophage

polarization, and type 1 and type 2 immune responses.
I make no apologies for the size and complexity of this text.
Immunology is a complex subject that has a direct bearing on many
of the most important areas of veterinary medicine. Students, as

well as graduate veterinarians, ignore it at their peril.
Finally, readers are strongly encouraged to visit the Evolve
website for this text. The site is also constantly evolving and
improving. In it you will be able to find a collection of more than

450 multiple-choice questions (with the answers!) keyed to each
chapter; a set of flashcards also linked to chapters; all the text
figures available as PowerPoint slides; and a collection of
animations kindly provided by Dr. Abul Abbas, as well as brand

new animations created for this textbook, designed to clarify some
complex processes and pathways where still figures are inadequate.
All the chapter references are keyed to PubMed. There are also new
hand-outs that students can print off and use as a reference, should

you wish. It is my hope that these assets will help you remain
current in this rapidly expanding and exciting field.
Ian Tizard

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