Page 620 - Veterinary Immunology, 10th Edition

VetBooks.ir Control of Immune Responses

Tolerance is not the only mechanism of immune regulation
employed by the body. The magnitude of immune responses must

also be regulated. An inadequate immune response may lead to
immunodeficiency and increased susceptibility to infection. An
excessive immune response may result in the development of
allergies or autoimmunity (Chapters 29 and 36). Failure to control
the lymphocyte proliferation that occurs during immune responses

may permit development of lymphoid cell tumors. Failure to
control the immune response to the fetus may lead to abortion
(Chapter 34). The immune responses must therefore be carefully

regulated to ensure that they are appropriate in both quality and
quantity. As might be anticipated, many different control
mechanisms exist.

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