Page 8 - The Toxicology of Fishes

Contents

Acknowledgments....................................................................................................... xi

The Editors ................................................................................................................xiii

Contributors ............................................................................................................... xv

Unit I. General Principles

1 Introduction ..........................................................................................................3
Richard T. Di Giulio and David E. Hinton

2 Bioavailability of Chemical Contaminants in Aquatic Systems ....................9
Russell J. Erickson, John W. Nichols, Philip M. Cook, and Gerald T. Ankley

3 Toxicokinetics in Fishes ....................................................................................55
Kevin M. Kleinow, John W. Nichols, William L. Hayton,
James M. McKim, and Mace G. Barron

4 Biotransformation in Fishes............................................................................153
Daniel Schlenk, Malin Celander, Evan P. Gallagher, Stephen George,
Margaret James, Seth W. Kullman, Peter van den Hurk, and Kristie Willett

5 Receptor-Mediated Mechanisms of Toxicity.................................................235
Mark E. Hahn and Eli V. Hestermann

6 Reactive Oxygen Species and Oxidative Stress............................................273
Richard T. Di Giulio and Joel N. Meyer

Unit II. Key Target Systems and Organismal Effects

7 Liver Toxicity ....................................................................................................327
David E. Hinton, Helmut Segner, Doris W.T. Au,
Seth W. Kullman, and Ronald C. Hardman

8 The Osmoregulatory System...........................................................................401
Sjoerd E. Wendelaar Bonga and Robert A.C. Lock

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