Page 252 - The Veterinary Care of the Horse
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        Figure 6.40a and b Pedal bone prolapsing through the sole of the foot: a) prolapsed pedal bone; b) the pedal bone has
        penetrated the sole (right), and a crescent-shaped area of imminent prolapse can be seen



             The disease can be divided into 3 stages:

        1    The developmental phase – this is the time when changes in the laminae begin but the
             horse is not yet showing any signs of pain.

        2    The acute  phase  starts  as  soon  as the  pain begins  and continues  until the pedal bone
             starts to move within the hoof capsule.

        3    The chronic  phase  includes  all  the  possible  subsequent  outcomes  from  mild  ongoing

             lameness to severe pain and penetration of the pedal bone through the sole of the foot.



        The important thing to remember is that by the time the horse or pony is showing signs of
        lameness,  damage  has  already  occurred  within  the  laminae  and  prompt  action  should  be

        taken to minimize the progress of the disease.
             Our  understanding  of  laminitis  is  increasing  all  the  time.  Whereas  it  was  traditionally

        associated with eating too much rich grass, it is now known that the majority of animals with
        laminitis have underlying hormonal conditions, which make them particularly susceptible to

        the  disease.  These  include  pituitary  pars  intermedia  dysfunction  (PPID,  also  known  as
        Cushing’s disease) and equine metabolic syndrome (EMS). Both of these diseases interfere

        with  the  normal  metabolism  of  insulin  and  this  is  known  as  insulin  dysregulation  (ID).
        Laminitis can also be triggered by sepsis (severe infection) or excessive weight-bearing on
        one limb, together with a number of other causes, which will now be looked at in more detail.
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