Page 87 - CL Armchair Case
P. 87

Shkreli, however, was in a hurry. Through Retrophin he

               made a $63 million purchase in February of Manchester

               Pharmaceuticals which helps illustrate Shkreli’s strategy of

               buying the rights to obsolete drugs and repurposing them


               as treatments for rare illnesses.



               Manchester’s main asset is Chenodal, an FDA-approved

               drug to treat gallstones that hadn’t caught on commercially.

               Chenodal, or chenodeoxycholic acid, can also be used to

               treat a rare disease called CTX, or cerebrotendinous

               xanthomatosis, which, if unaddressed, can cause brain


               damage and early death. The FDA has granted Chenodal

               orphan drug status for CTX patients, meaning that for a

               period of years, its owner receives valuable financial

               incentives to proceed.
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