Page 90 - The Manga Guide to Biochemistry
P. 90

Electron
                                                                      transport chain

                Proton                           Proton

                                                                      Alright!

                What happens to the electrons
                 (e-) and protons (H+) that were

                   "deposited" in NAD+ and FAD?
                                      Let's take a look!

intermembrane   electron                         Cytochrome C                   ATP         inner
        space      flow                            Complex III            synthase      membrane of
                                                                                     mitochondria
Complex I                                  Co Q                       Complex IV

 Matrix

                   An electron directly enters the electron
                transport chain and, as you might guess from

                   the name, is transported between several
                                         protein complexes.

    protons                                      Cytochrome C              ATP              inner
  collected                                                           synthase          membrane of
 in the inter­                                                                       mitochondria
   membrane

       space

intermembrane
        space

Complex I

                        Co Q                             Complex III

Matrix

                                                                      Complex IV

        While this electron (e-) is successively transferred,                        interesting...
               the proteins undergo various changes. As a

          result, protons (H+) move from the mitochondrial
           matrix to the intermembrane space (between the
            inner and outer membranes). Three "pumps" push

              these protons into the intermembrane space.
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