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Cashew is Healthy for the Entire Family

The Effects of Cashew Nut Intake on Lipid Profile and

Blood Pressure: A Systematic Review and Meta-Analysis

of Randomised Controlled Trials

Cashew and Blood Pressure

Author(s): Mohammad Jalali, Seyedeh Parisa Moosavian, Morteza Zare ,
Malihe Karamizadeh , Gordon A Ferns, Marzieh Akbarzadeh

Author Affiliation: Student Research Committee, Shiraz University of Med-
ical Sciences, Shiraz, Iran; Electronic address: m_akbarzadeh@sums.ac.ir;
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz Uni-
versity of Medical Sciences, Shiraz, Iran; Brighton & Sussex Medical School,
Division of Medical Education, Falmer, Brighton, Sussex, UK; Department of
Clinical Nutrition, School of Nutrition and Food Science, Food Security Re-
search Center, Isfahan University of Medical Sciences, Isfahan, Iran.

• PMID: 32444052 DOI: 10.1016/j.ctim.2020.102387 Results: A meta-analysis of 392

participants showed that cashew
Abstract nut consumption had no signif-
Background: Dyslipidemia and hypertension are important risk factors for
icant effects on lipid profile and
cardiovascular disease (CVD). Some studies have suggested that the con- DBP. However, there was a signifi-
sumption of nuts may reduce CVD risk.
cant reduction in SBP (WMD =
Objective: The present systematic review and meta-analysis were conduct- -3.39, 95 % CI = [-6.13, -0.65], P
ed to investigate the efficacy of cashew nut consumption on lipid profile and
= 0.01, I2 = 0.0 %) in the group
blood pressure. receiving cashew nuts compared
to the controls. There was no
Methods: PubMed, Embase, Scopus, Web of Science and Cochrane Library significant publication bias in the
were systematically searched to identify randomized control trials (RCTs)
meta-analysis. A sensitivity anal-
examining the effects of cashew nut intake on serum triglycerides (TG), high ysis showed that omitting each
density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol
study did not change the signifi-
(LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or dia- cance of the results.
stolic blood pressure (DBP) until 15 November 2019. A random-effects model
was used to pool weighted mean difference (WMD) and 95 % confidence
intervals (CI). Potential publication bias was assessed using Egger's test.
Conclusion
Sensitivity analysis was performed to assess the impact of each individual This meta-analysis demonstrated that
study on the pooled results.
cashew nut consumption might reduce
SBP but does not affect lipid profile
Keywords: Blood pressure; Cashew nut; Lipid profile; Meta-analysis; Review.
and DBP.
Copyright © 2020 Elsevier Ltd. All rights reserved.

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