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Cashew is Healthy for the Entire Family

Cashew Nut Consumption Increases HDL Cholesterol and

Reduces Systolic Blood Pressure in Asian Indians with

Type 2 Diabetes: A 12-Week Randomized Controlled Trial

Cashew and Cholesterol
and Type 2 Diabetes

Author(s): Viswanathan Mohan, Ranjit Mohan Anjana , Rajagopal Gayathri,
Results: Participants in the
Nagarajan Lakshmipriya, Raman Ganesh Jeevan, Kandappa K Balasubra- intervention group had a great-
maniam, Parthasarathy Vijayalakshmi, Mookambika Ramya Bai R,
er decrease in systolic blood
Vasudevan Sudha, Kamala Krishnaswamy, Donna Spiegelman, Jordi pressure from baseline to 12
Salas-Salvadó, Walter C Willett
weeks than did controls (–4.9 ±
13.7 compared with –1.7 ± 11.6
Author Affiliation: Departments of Diabetology and Foods, Nutrition &
mm Hg; P = 0.04) and a greater
Dietetics Research, Madras Diabetes Research Foundation, Chennai, Tamil increase in plasma HDL cho-
Nadu, India; Departments of Global Health and Population, Nutrition, and
lesterol compared with controls
Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA and (+1.7 ± 5.6 compared with +0.1
Human Nutrition Unit, Hospital Universitari Sant Joan de Reus, Biochemis-
± 4.6 mg/dL; P = 0.01). There
try and Biotechnology Department, IISPV, Universitat Rovira i Virgili, Reus, were no differences between the
Spain, and CIBERobn Physiopathology of Obesity and Nutrition, Instituto de
groups with respect to changes in
Salud Carlos III, Madrid, Spain
body weight, BMI, blood lipid, and
glycemic variables. Plasma oleic
acid concentrations and self-re-
Abstract
ported dietary intake of nuts, oleic
Background: There is increasing evidence that nut consumption decreas- acid, and monounsaturated fatty
es the risk of cardiovascular disease. However, there are few data on the
acids suggested excellent compli-
health effects of cashew nuts among adults with type 2 diabetes (T2DM).
ance with the nut consumption

Objective: The study aimed to investigate the effects of cashew nut sup-
plementation on glycemia, body weight, blood pressure, and lipid profile in
Asian Indians with T2DM. Methods: In a parallel-arm, randomized con- Conclusion
trolled trial, 300 adults with T2DM [mean ± SD age: 51 ± 9.3 y; body mass Cashew nut supplementation in Asian
index (BMI; in kg/m2): 26.0 ± 3.4; 55% male] were randomly assigned to Indians with T2DM reduced systolic
receive advice to follow a standard diabetic diet (control) or similar advice blood pressure and increased HDL
plus 30 g cashew nuts/d (intervention) for 12 wk. cholesterol concentrations with no del-
eterious effects on body weight, glyce-
The macronutrient composition of the prescribed diabetic diet was 60–65% mia, or other lipid variables. This study
energy from carbohydrates, 15–25% from fat, and the rest from protein. was registered at the clinical trial regis-
Differences between groups in changes in anthropometric and biochemical try of India as CTRI/2017/07/009022.
variables were analysed using linear models with robust variance estimation J Nutr 2018;148:63–69.
under an assumed independence working correlation.

Keywords: body weight; cashew nut; high-density lipoprotein cholesterol;
type 2 diabetes.

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