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Clinical pharmacy PharmD program Third level Phytochemistry-1 (PG-504)

Hydrolysis:

Sinigrin gives upon hydrolysis: allyl isothiocyanate (volatile oil of mustard), glucose, as well as
potassium acid sulfate.

Uses:

Black mustard and white mustard seeds are used as rubefacients and counter irritants , and
these effects are attributed to their contents of thioglycosides.

Phenolic Glycosides

The phenolic aglycones are classified into:

1. Simple phenolic glycosides.

2. Coumarin glycosides

3. Lignans and neolignans

4. Anthraquinones glycosides

5. Flavones and related flavonoid glycosides

1. Simple Phenolic Glycosides

1-Salicin 2-Coniferin 3- Arbutin

Source: bearberry (Uva ursi) leaves.

Hydrolysis: acids or emulsin it yields hydroquinone

and glucose.

Chemical test: + FeCl3 gives vi olet col.

Uses:

1. diuretic

2.renal antiseptic is due to the hydroquinone given by hydrolysis.

3. Arbutin is used for skin whitening. It is proved to be a good inhibitor for melanin
synthesis and may be used in hyperpigmentation disorders.

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