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Clinical pharmacy PharmD program                     Third level                          Phytochemistry-1 (PG-504)






              Second degree of unsaturation                p-menthadiene







           1,3                 2,5                 1,8 ∆                1,4(8)                1(7),2
                ∆                 ∆                                           ∆                     ∆


                          1,8
              Limonene (∆ -p-menthadiene)
              Source: Many oils as citrus fruits rind oils

              Present as d-liomnene or l-limonene or dl mixture (dipentene)

              Uses:  - In cosmetics, perfumary and food manufacturing.

                 -  Flavouring and masking agent in medicines.

                 -  It dissolves gall bladder stones (Rowachol)

                 -  Helpful in the treatment of hyperchlesterolemia

                 -  Botanical Insecticide (d-liomnene is more active than l-limonene).
                 -  Moisture and Air cause changes in the composition of some oils on storage.




















              Terpinolene (∆ 1,4(8) -p-menthadiene)
              Source: Coriander, cardomom, Marjoram and orange oils

              Uses: Scenting (perfumes), cosmetics, food Industries.


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