Page 292 - Pharmacognosy 2 PG303 (1)

Pharmacognosy-2 (PG303) Level 2 Clinical Pharmacy-Pharm D

Chemical ➢ On micro- ■ Test for
tests sublimation , Anthraquinones
powdered (Bornträger's test) :
Hydrastis yields a pink color in the
yellow crystalline ammoniacal layer
sublimate of (aqueous layer)
hydrastine . ■ Others???
➢ Shake powdered ❖ Rheum raponticum
Hydrastis with contains rhaponticin
CHCl3 filter, which is a stilbene
evaporate the derivative that has
filtrate to dryness, estrogenic effect .

▪ Residue + H2SO4 + ➢ It can be detected in
small crystal of the official drug by:
ammonium ✓ It gives blue
molybdate ,a green fluorescence in UV
color changed to radiation unlike
blue. rhubarb gives reddish

▪ Residue + H2SO4 + brown fluorescence .
few drops of ✓ Furfural test:
bromine ,a blood- furfural dps of
.
+
red color is conc .H₂SO₄ little
+
produced . powder if rhapontic
gives
violet color .

Uses ▪ anti -inflammatory ▪ Expectorant : ■ Depending on the ▪ It resembles digitalis Rat poison

for the uterine used in bronchitis dose ,rhubarb can be in its action on the (Rodenticide)
mucous membrane . ▪ Emetine has used as: heart .It increases the

.
▪ isoquinoline alkaloid amoebicidal activity - Laxative )1-2 g) strength and reduces
constituents ▪ Larger amount of - Astringent and the frequency of the
(Antibiotic , the drug is a strong stomachic )0.1-0.2g) cardiac action .

Immunostimulant , emetic . ▪ It is a powerful
Anticonvulsant , expectorant &

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