Page 7 - SONO 260 Chapter 25 The Fetal Face and Neck
P. 7
Fetal Mouth, Lip, and
Mandible
▪ The fetal lip typically closes between 7 and 8 weeks, while the palate closes by 12 weeks.
▪ An abnormal closure or incomplete closure of lip and palate results in cleft lip and cleft palate, respectively.
▪ These two abnormalities may exist together or as isolated findings.
▪ Cleft lip and cleft palate are among the most common congenital abnormalities and have been associated with many syndromes and congenital anomalies, such as holoprosencephaly, trisomy 13, and amniotic band syndrome, although the majority of cases are not associated with any other abnormalities.
