Page 108 - Medical Parasitology_ A Textbook ( PDFDrive )

Filarial Worms Causing Lymphatic Filariasis 101

Wuchereria bancrofti
Mosquito Stages 1 Mosquito takes Human Stages
a blood meal
(L3 larvae enter skin)
8 Migrate to head and
mosquito’s proboscis

7 L3 Larvae i
2 Adults in lymphatics

Adults produce
6
L1 Larvae sheathed microfilariae
3
that migrate into lymph
Mosquito takes
4 a blood meal and blood channels
(ingests microfilariae) d
5 Microfilariae shed sheaths,
penetrate mosquito’s midgut,
and migrate to thoracic muscles
i = Infective Stage
d = Diagnostic Stage
Brugia malayi
Mosquito Stages 1 Mosquito takes Human Stages
a blood meal
(L3 larvae enter skin)
8 Migrate to head and
mosquito’s proboscis

7 L3 Larvae i
2 Adults in lymphatics

6
L1 Larvae
Adults produce
3 sheathed microfilariae
Mosquito takes that reach the blood
4 a blood meal stream
5 Microfilariae shed sheaths, (ingests microfilariae) d
penetrate mosquito’s midgut,
and migrate to thoracic muscles

i = Infective Stage
d = Diagnostic Stage
Fig. 10.15 Life cycle of Wuchereria bancrofti and Brugia malayi (Reproduced from https://www.
cdc.gov/dpdx/lymphaticfilariasis/index.html)