Page 21 - Medical Parasitology_ A Textbook ( PDFDrive )

Naegleria fowleri 13

5
6
Amoebae penetrate
the nasal mucosa
Amoebae migrate to the brain via
the olfactory nerves causing
primary amoebic meningoencephalitis
(PAM) in healthy individuals
Trophozoites in CSF and
Water-related activities brain tissue
such as swimming Flagellated forms d
underwater, diving occasionaly in CSF
or other water sports
can result in water
going up the nose

1 Cyst

i = Infective Stage
d = Diagnostic Stage
4
Promitosis
2
Trophozoite i

3
Flagellated form
Fig. 3.5 Life cycle of Naegleria fowleri (Reproduced from https://www.cdc.gov/dpdx/freeliving-
amebic/index.html)