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Intestinal Nematodes: Soil-Transmitted Helminths (STH) 83

a b

c

Fig 10.3 Ascaris lumbricoides. (a) Adults, (b) Fertilized egg, (c) Unfertilized egg

Two types of eggs are passed by the female worm; fertilized and unfertilized.
The fertilized egg is spherical or ovoid, bile stained, measuring 60–75 μm in length
with the ovum inside (Fig. 10.3b). The outer layer is coarsely mamillated. The
unfertilized egg is longer, more elliptical with a thinner shell, measuring up to
90 μm and contains granules (Fig. 10.3c). It does not develop into the infective
stage.

Life Cycle (Fig. 10.4)
(1) The adult male and female worms live in the lumen of the small intestine of
human. (2) The female worm produces both fertilized and unfertilized eggs which
are passed out in faeces. (3) In the soil, the fertilized egg undergoes development
to the infective stage. (4) Human acquires infection via ingestion of the infective
eggs. (5) In the intestine, the eggs hatch into larvae. (6) The larvae penetrate the
mucosa of the small intestine and enter the portal circulation and are carried to the
heart and lungs. (7) In the lungs, the larvae rupture out of the alveolar capillaries
into the alveolar space and crawl up the bronchiole, bronchi, trachea and pharynx.
They are swallowed back into the intestine where they develop into adults in about
3 months.