Page 360 - Pharmacognosy 2 PG303
P. 360
Level 2 Clinical Pharmacy-Pharm D
osides, Opium is a complex mixture of an active alkaloid
ytic fraction (10-20%), together with sugars, protein,
lipids and other gummy substances. The most
s it improves the important are 5 major alkaloids:
tivity by • Phenanthrane group:
and has emollient
morphine, codeine and thebaine.
• Isoquinoline group:
• papaverine and noscapine (narcotine).
Opium is used as a source of
• morphine (analgesic)
• codeine (cough sedative)
• papaverine (antispasmodic for smooth muscle).
in → cool +
the following tests for Ferric Chloride Test:
(Meconic acid test):
ating → transfer 5-10 5% Aqueous solution of FeCl3 to an alcoholic
ed with water extract of opium,
o the formation of a brownish purple color Indicates the possible
presence of opium.
barbaloin by
of ether layer with 10
oniacal layer.
er test):
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