Page 360 - Pharmacognosy 2 PG303
P. 360

Level 2                  Clinical Pharmacy-Pharm D

osides,                  Opium is a complex mixture of an active alkaloid
ytic                     fraction (10-20%), together with sugars, protein,
                         lipids and other gummy substances. The most
s it improves the        important are 5 major alkaloids:
tivity by                • Phenanthrane group:
 and has emollient
                              morphine, codeine and thebaine.
                         • Isoquinoline group:
                         • papaverine and noscapine (narcotine).

                         Opium is used as a source of
                         • morphine (analgesic)
                         • codeine (cough sedative)
                         • papaverine (antispasmodic for smooth muscle).

in → cool +

the following tests for Ferric Chloride Test:
                           (Meconic acid test):

 ating → transfer 5-10   5% Aqueous solution of FeCl3 to an alcoholic
 ed with water           extract of opium,
o the formation of       a brownish purple color Indicates the possible
                         presence of opium.
 barbaloin by

 of ether layer with 10

oniacal layer.
er test):

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