Page 38 - final Practical handout PG 303-Cogno-2- 2024-2025
P. 38

Clinical Pharm D                             Level 2      Pharmacognosy-2 (PG 303)

 Item                       Subterranean drugs         Rhubarb ‫الراوند‬
                  Liquorice ‫عرق سوس‬

Macroscopical
  characters

                    Cylindrical pieces.                Rectangular pieces (barrel).
                    Very sweet taste.                  Bitter with slight astringent taste.
                                                       Gritty under teeth??
                    Fracture: fibrous in bark,         Colors saliva yellow
                    splintery in wood.
                                                         Fracture: granular (not fibrous).
                    ✓ With 1-2 drops of 66%
                        H₂SO₄, an orange red color is  ✓ Micro sublimation: powdered
                        produced.                         Rhubarb gives a yellow needle
                                                          shaped sublimate which
                    ✓ With water, a voluminous            dissolves in KOH give red
                        froth is produced.                color.

                    ✓ With Fehling reagent on W.B      ✓ Borntrager’s test: Shake
Chemical tests give a red ppt. due to reducing            powder with ether, take ether
                                                          layer with aq. NH₄OH gives
                        sugars.                           red color.

                                                       ✓ Alcoholic extract in UV light
                                                          gives brown color.

                                                       ✓ FeCl₃ test (gallotannins) gives
                                                          bluish black color.

                                Rhapontic rhubarb

◼ Rhaponticin which is a stilbene derivative that has estrogenic effect.
◼ It gives blue fluorescence in UV radiation unlike rhubarb gives brown

   fluorescence.

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