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               Clinical Pharmacy-Pharm D        Level Three        2  Semester       2024/2025      Pharmaceutical Technology (PT 607)


               Problems on sieving and microscopy



                   1.  A powder size analysis was carried out on 192 gm powder A using the
                       sieve method, the following data were obtained

                   •  Draw a cumulative % frequency under and over size
                   •  Calculate the mean granule diameter
                                      Med point of            Weight retained
                                        size range               Frequency
                                                                      (n)

                                            250                        0
                                            180                       4.1

                                            125                       8.4
                                             90                      13.7
                                             75                      15.4
                                             53                      32.7
                                             20                     117.7

               Solution

                     Med point        Weight        Cumulative  Cumulative  Cumulative
                        of size       retained          mass          % Over        % Under size
                        range        Frequency        retained           size
                                         (n)

                         250              0
                         180             4.1
                         125             8.4
                          90            13.7
                          75            15.4
                          53            32.7
                          20            117.7



















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