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structure allows asbestos to trap heat, muffle sound, and resist   milk of European mothers have fallen substantially. In the
                        fire. Because of these qualities, asbestos was used widely as   United States, however, there has so far been little movement
                        insulation in buildings, as well as in other products. Unfor-  to address the issue. The dangers posed by fire retardants such
                        tunately, its fibrous structure also makes asbestos dangerous   as PBDEs have caused some to question the stringent flam-
                        when inhaled. When asbestos gets lodged in lung tissue, the   mability standards that often make the use of such chemicals
                        body produces acid in an attempt to eliminate it. The acid   necessary. As stated by Linda Birnbaum of the National Insti-
                        scars the lung tissue but does little to dislodge or dissolve the   tute of Environmental Health Sciences, “I don’t question the
                        asbestos. Within a few decades, the scarred lungs may cease   need for flame retardants in airplanes, but do we need them in
                        to function—a disorder called asbestosis. Asbestos can also   nursing pillows and babies’ strollers?”
                        cause certain types of lung cancer. Because of these risks,
                        asbestos has been removed from many schools and offices.   Risks must be balanced against rewards
                        However, the removal process can release some asbestos into
                        the air, increasing people’s exposure, so in some cases the   The job of toxicologists and other scientists who study envi-
                        best approach is to encase the material in place.    ronmental health hazards is to learn as much as they can about
                            Lead poisoning is another indoor health hazard. When   the hazards, but the rest of us need to take this information
                        ingested, lead, a heavy metal, can cause damage to the brain,   and weigh it against any benefits we obtain from exposing
                        liver, kidney, and stomach; learning problems and behavio-  ourselves to the hazards. With most hazards, there is some
                        ral abnormalities; anemia; hearing loss; and even death. Lead   tradeoff between risk and reward, and we must judge as best
                        poisoning among U.S. children has greatly declined in recent   we can how these compare. In regard to bisphenol A, its use-
                        years as a result of education campaigns and government reg-  fulness for many purposes means that despite its health risks,
                        ulations that phased out lead-based paints and leaded gasoline   we may as a society choose to continue using it. The avail-
                        starting in the 1970s. Today lead poisoning can result from   ability of safer and affordable alternatives is important in such
                        drinking water that has passed through the lead pipes common   decisions. Industry is finding replacements for BPA polymers
                        in older homes or from ingesting or inhaling lead-containing   in baby bottles and water containers, but until a replacement
                        dust produced by the slow wearing-away of leaded paint.  is found for it as an epoxy liner for food cans, it will likely
                            We have succeeded in removing significant sources of   continue to serve this function.
                        lead exposure in the United States, but modern Americans are   As we review the impacts of toxic substances throughout
                        still exposed to elevated levels of lead. For example, millions   this chapter, it is important to keep in mind that artificially
                        of children’s toys and other items exported from China were   produced chemicals have played a crucial role in giving us
                        found to contain lead-based paint in recent years. The result-  the standard of living we enjoy today. These chemicals have
                        ing consumer outcry in the United States forced recalls of   helped create the industrial agriculture that produces our food,
                        these items, and China eventually agreed to limit and monitor   the medical advances that protect our health and prolong our
                        the use of lead-based paint in its manufacturing.    lives, and many of the modern materials and conveniences we
                            In 2012, the Centers for Disease Control (CDC) adopted   use every day. It is appropriate to remember these benefits
                        an advisory panel’s recommendation and lowered the danger   as we examine some of the unfortunate side effects of these
                        threshold for lead levels in children’s blood from 10 micro-  advances and as we search for better alternatives.
                        grams/deciliter to 5 micrograms/deciliter. This decision was
                        based on numerous studies that showed adverse effects of lead
                        on neurological development at blood lead levels below the   Toxic Substances and Their
                        previous standard.                                   Effects on Organisms
                            One recently recognized hazard is a group of chemicals
                        known as  polybrominated diphenyl ethers (PBDEs). These
                        compounds provide fire-retardant properties and are used in   Our  environment  contains  countless  natural  substances  that
                        a diverse array of consumer products, including computers,   may pose health risks. These include petroleum, oozing natu-
                        televisions, plastics, and furniture. They are emitted during   rally from the ground; radon gas, seeping up from bedrock;
                        production and disposal of products and may also release   and  toxins, toxic chemicals manufactured in the tissues of   CHAPTER 14 • Envi R onm E n TA l H EA lTH   A nd T o xi C ology
                        into the air at very slow rates throughout the lifetime of prod-  living organisms. For example, toxins can be chemicals that
                        ucts. These chemicals persist and accumulate in living tissue,   plants use to ward off herbivores or that insects use to defend
                        and their abundance in the environment and in people in the   themselves  from  predators.  In addition,  we  are  exposed  to
                        United States is doubling every few years.           many synthetic (artificial, or human-made) chemicals, some
                            Like bisphenol A, PBDEs appear to act as hormone dis-  of which also have toxic properties.
                        ruptors; lab testing with animals shows them to affect thyroid
                        hormones. Animal testing also suggests that PBDEs affect the   Synthetic chemicals are all around
                        development of the brain and nervous system and may cause   us—and in us
                        cancer. Concern about PBDEs rose after a study showed that
                        concentrations in the breast milk of Swedish mothers had   Tens of thousands of synthetic chemicals have been manu-
                        increased exponentially from 1972 to 1997. U.S. studies also   factured (TAble 14.2), and synthetic chemicals surround us in
                        show rising concentrations in breast milk.  The   European   our daily lives. Each year in the United States, we manufac-
                        Union  decided  in  2003  to  ban  PBDEs,  and  industries  in   ture or import 113 kg (250 lb) of chemical substances for
                        Europe phased them out. As a result, concentrations in breast   every man, woman, and child. Many of these substances find   385







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