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Industry and manufacturing

                                   Consumer products  Workplace products   Medicines and materials   Pesticides and fertilizers   Waste   Waste   Waste















                                                     Medical facilities  Agriculture: crops,        Water: surface
                            Home           Work      and public spaces  rangeland, feedlots  Soil  and groundwater      Air







                                                                   Food                       Plant growth
                                            Workplace exposure
                                                                    Drinking water   Non-target effects      Drinking water   Air for breathing
                                Consumer products
                                                            Medicines and materials
                                                                    Air for breathing




                                                       Humans       Hunting and harvesting
                                               Genes, womb,
                                               breast milk



                                                                                             Nonhuman biota
                                               Human fetuses and babies
                        Figure 14.12 Synthetic chemicals take many routes in traveling through the environment. People take
                        in only a tiny proportion of these compounds, and many compounds are harmless. However, people receive
                        small amounts of toxicants from many sources, and developing fetuses and babies are particularly sensitive.




                        chemicals such as DDT and PCBs persist for decades. Atra-  Toxicants may accumulate and move              CHAPTER 14 • Envi R onm E n TA l H EA lTH   A nd T o xi C ology
                        zine, our most widely used herbicide, is highly variable in its   up the food chain
                        persistence, depending on environmental conditions.
                            Persistent synthetic chemicals exist in our environment   Of  the  toxic  substances  that  organisms  absorb,  breathe,  or
                        today because we have designed them to persist. The synthetic   consume, some are quickly excreted, and some are degraded
                        chemicals used in plastics, for instance, are used precisely   into harmless breakdown products. Others persist intact in the
                        because they resist breakdown. Sooner or later, however, most   body. Substances that are fat-soluble or oil-soluble (including
                        toxicants degrade into simpler compounds called breakdown   organic compounds such as DDT and DDE) are absorbed and
                        products. Often these are less harmful than the original sub-  stored in fatty tissues. Substances such as methylmercury
                        stance, but sometimes they are just as toxic as the original   (CH Hg ) may be stored in muscle tissue. Such persistent
                                                                                    +
                                                                                 3
                        chemical, or more so. For instance, DDT breaks down into   toxicants accumulate in an animal’s body in a process termed
                        DDE, a highly persistent and toxic compound in its own right.   bioaccumulation, such that the animal’s tissues have a greater
                        Atrazine produces a large number of breakdown products   concentration of the substance than exists in the surrounding
                        whose effects have not been fully studied.           environment.                                         391







           M14_WITH7428_05_SE_C14.indd   391                                                                                    12/12/14   3:04 PM
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