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xvi Contents

31.	 Cost-Eff ectiveness of HPV Vaccination . . . . . . . . . 309                         50.	 Compartment Resection in
                                                                                                 Gynaecologic Oncology: TMMR and LEER . . . . . . 450
        Mireia Diaz, PhD, Claudia Robles, PhD
        Silvia de Sanjosé, MD and F. Xavier Bosch, MD                                             Michael Höckel, MD, Rainer Kimmig, MD

32.	 Immune Therapies for Human                                                           51.	 Nerve-Sparing Surgery in
       Papillomavirus-Induced Diseases . . . . . . . . . . . . . . 321                           Cervical Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . 455

        Sjoerd H. van der Burg, PhD                                                               Shingo Fujii, MD, Kentaro Sekiyama, MD

33.	 Cervical Pre-Invasive Disease . . . . . . . . . . . . . . . . . . 329                52.	 Neoadjuvant Chemotherapy in
                                                                                                 Cervical Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . 463
        Vesna Kesić, MD, PhD
                                                                                                  Roberto J. Vargas, MD, Peter G. Rose, MD
34.	 Cervicovaginal Cytology: Normal and
       Abnormal Cells and Adequacy of Specimens  . . . 336                                53.	 Concomitant Chemotherapy in
                                                                                                 Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471
        Christine Bergeron, MD, PhD
                                                                                                  Giovanni Scambia MD, Giulia Amadio MD
35.	 The Basic Principles of Colposcopy  . . . . . . . . . . . . 343                              Gabriella Ferrandina MD

        Claire Bailey, MRCOG, David Luesley, MA, MD, FRCOG                                54.	 Systemic Therapy for Recurrent and
                                                                                                 Metastatic Cervical Cancer 1st Line
36.	 Picture Gallery for Abnormal Cytology                                                       Anti-Angiogenesis Therapy and
       and Colposcopic Findings . . . . . . . . . . . . . . . . . . . . . 348                    Translational Rationale for Emerging 2nd
                                                                                                 Line Therapies  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 476
        Ermina Iljazović, MD, PhD, Azra Sadiković, MD
        Maja Konrad-Čustović, MD                                                                  Krishnansu S. Tewari, MD, FACOG, FACS
                                                                                                  Bradley, J. Monk, MD, FACOG, FACS
37.	 How to Manage Pre-Invasive
       Cervical Diseases? An Overview . . . . . . . . . . . . . . . 357                   55.	 Radiotherapy for Cervical Cancer . . . . . . . . . . . . . . 487

        Mufit C. Yenen, MD, Ulas Fidan MD, Firat Ortac, MD                                        Mansoor R. Mirza, MD, Ivan Richter Vogelius, PhD
        Murat Dede, MD, Mete Gungor MD.                                                           Taran P. Hellebust, PhD

38.	 Destructive Techniques for Cervical                                                  56.	 Local Management of Relapse in
       Preinvasive Lesions . . . . . . . . . . . . . . . . . . . . . . . . . . . 363             Cervical Cancer With Radiotherapy . . . . . . . . . . . . 495

        Liidia Gristsenko, MD, Kersti Kukk, MD                                                    Megan Llewelyn, MBBS, Alexandra Taylor, MBBS, MD

39.	 Excisional Techniques for                                                                                     SECTION III:
       Cervical Preinvasive Lesions  . . . . . . . . . . . . . . . . . . 366                           DISEASES OF UTERINE CORPUS

        Gokhan Tulunay, MD, Nejat Ozgul, MD                                               57.	 Endometrial Hyperplasia Without
                                                                                                 Atypia and Endometrioid Intraepithelial
40.	 Management of Positive Resection                                                            Neoplasia (EIN) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509
       Margin After Treatment for
       Cervical Precancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372             George L. Mutter, MD

        Fuat Demirkiran, MD                                                               58.	 Treatment of Endometrial Hyperplasia . . . . . . . . 516

41.	 The Pathology of Cervical Cancer . . . . . . . . . . . . . . 376                             George Vorgias, MD, PhD, Stelios Fotiou, MD, PhD

        Michael Scott, MD, FRCPath                                                        59.	 Hysteroscopy in Endometrial Cancer . . . . . . . . . . . 522

42.	 Management of Small                                                                          Milos Mlyncek, MD, PhD, Erik Lajtman, MD, PhD
       Volume Cervical Cancers . . . . . . . . . . . . . . . . . . . . . . 381
                                                                                          60.	 Endometrial Cancer:
        Akira Kurosaki, MD, PhD, Kosei Hasegawa, MD, PhD                                         Epidemiology and Treatment  . . . . . . . . . . . . . . . . . 529
        Keiichi Fujiwara, MD, PhD
                                                                                                  Stefano Uccella, MD, PhD, Fabio Ghezzi, MD
43.	 Radical Vaginal Trachelectomy . . . . . . . . . . . . . . . . 387                            Jvan Casarin, MD, Francesco Multinu, MD
                                                                                                  Jamie N. Bakkum-Gamez, MD, Andrea Mariani, MD
        Christhardt Köhler, MD, Giovanni Favero, MD
        Achim Schneider, MD, MPH                                                          61.	 Histopathology of Endometrioid
                                                                                                 Endometrial Cancer  . . . . . . . . . . . . . . . . . . . . . . . . . . 539
44.	 Chemo-Conization for Early Staged
       Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398          Tjalling Bosse, MD, PhD

        Anna Festi, MD, Fabio Landoni, MD                                                 62.	 Uterine Sarcomas  . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543

45.	 Surgery in Bulky Cervical Cancer  . . . . . . . . . . . . . . 406                            Esther Oliva, MD

        Christhardt Köhler, MD, Giovanni Favero, MD                                       63.	 Treatment of Advanced and Recurrent
        Achim Schneider, MD, MPH, Simone Marnitz, MD                                             Endometrial Cancers . . . . . . . . . . . . . . . . . . . . . . . . . . 550

46.	 Management of Locally Advanced                                                               Ingrid Vandenput, MD, Lieve Coenegrachts, MD
       Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422          Frederic Amant, MD, PhD

        Christine Haie-Meder, MD, Cyrus Chargari, MD, PhD                                 64.	 Compartment Resection in
        Renaud Mazeron, MD, PhD, Philippe Morice, MD, PhD                                        Endometrial Cancer: Peritoneal
                                                                                                 Mesometrial Resection (PMMR) and
47.	 The Role of Lymph Node Dissection in                                                        Therapeutic Lymphadenectomy . . . . . . . . . . . . . . . 558
       Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432
                                                                                                  Rainer Kimmig, MD, Bahriye Aktas, MD
        Cecilia Escayola Vilanova, MD, Denis Querleu, MD                                          Martin Heubner, MD

48.	 Management of Incompletely Operated
       Cervical Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436

        Gustavo Leme Fernandes, MD
        Adriana Bittencourt Campaner, MD, PhD

49.	 Sentinel Lymph Node in Cervical Cancer . . . . . . . 440

        Cagatay Taskiran, MD, Selim Misirlioglu, MD, Anil Onan, MD
        Haldun Guner, MD, Ali Ayhan, MD
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