Page 7 - Uro_Onco_booklet

Part 3: Value and Use of Predictive Markers in mCRPC

Factors for the choice of first-line treatment options:

Moderately
Important Less important
factors a important factors c
factors b
Neutrophil-
Gleason score (i.e.
Response to < 8 vs ≥ 8) lymphocyte ratio
primary ADT (i.e. ≤ (NLR)
12 months vs > 12 Presence
months) of visceral Age
metastases
Performance
Presence of AR- status Presence of bone
splice variants Presence of co- metastases
morbidities

a having potentially predictive effects on first-line treatment options
b solely providing prognostic information that might not affect treatment options
c having neither predictive nor prognostic effects

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