Page 132 - Design in Nature
P. 132

A System Without Room for

                  Smallest Error: Blood Clotting



                       Everybody knows that bleeding will eventually stop when
                  there is a cut or when an old wound starts bleeding again.

                  Where the bleeding is, a blood clot forms that hardens and heals
                  the wound in due time. This may be a simple and normal
                  phenomenon for you, but biochemists have shown through
                  their research that this actually is the result of a very
                  complicated system at work. The lack of any one component of
                  this system or any damage to it would render the whole process
                  useless.
                       Blood has to coagulate in the right time and place and
                  when normal conditions are restored, the clot should vanish.
                  The system functions flawlessly down to the minutest detail.
                       If there is bleeding, the clot should form immediately in
                  order to prevent the creature from dying. Furthermore, the clot
                  should cover the entire wound and, more importantly, should
                  only form over, and remain right on top of, the wound.

                  Otherwise all the blood of the creature could coagulate and
                  cause its death, which is why the clot should form at the right
                  time at the right place.
                       The smallest elements of the bone marrow, the blood
                  platelets or thrombocytes, are crucial. These cells are the main
                  elements behind the coagulation of blood. A protein, called the
                  Von Willebrand factor, ensures that, in their continuous patrol of
                  the blood stream, these platelets do not miss the place of the
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