Page 138 - 2019秋季手冊內頁-ebook測試
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Variables in Clinical and Preclinical Modeling
Murine Tumor Models Clinical Cancer PLaifteiePnhatse in Human and Mice
• Vary but generally >55 years old
• Increasingly obese
• Variety of chronic infections
and diseases
• 8-12 weeks old (equivalent to a young adult)
• Lean
• Specific pathogen free
Variables in Clinical and Preclinical Modeling
Murine Tumor Models Clinical Cancer PLaifteiePnhatse in Human and Mice
• Vary but generally >55 years old
• Increasingly obese
• Variety of chronic infections
and diseases
• Outbred population with progressive heterogenous tumors
• 8-12 weeks old (equivalent to a young adult)
• Lean
• Specific pathogen free
• In vitro tumor cell lines into healthy naive mice
139
