Page 25 - International guidelines for groin hernia management
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Hernia

           surgery, those techniques are probably also cost effective  laparo-endoscopic procedures when compared with the
           and very safe. However, many of the studies in this area  Lichtenstein repair including: a lower incidence of wound
           suffer from weakness such as: lack of clear endpoints in  infection (OR 0.39; 95% CI 0.26–0.61; p = 0.00003), a
           pain assessment, definitions, quality of the surgeon’s  reduction in hematoma formation (OR 0.69; 95% CI
           technique and caseload per surgeon. Additionally, there is a  0.54–0.90; p = 0.005), and nerve injury (OR 0.46; 95% CI
           well-documented difference in learning curve and initial  0.35–0.61; p \ 0.00001), an earlier return to normal
           costs favoring Lichtenstein.                       activities or work (- 1.35; 95% CI - 1.72 to - 0.97;
             In order to properly address the key question, all meta-  p \ 0.00001), and fewer incidences of chronic pain syn-
           analyses and RCTs must be excluded that compared   drome (OR 0.56; 95% CI 0.44–0.70; p \ 0.00001). 244  No
           laparo-endoscopic techniques with either, open techniques  difference was found in total morbidity or in the incidence
           other than Lichtenstein, and/or those that enrolled patients  of intestinal lesions, urinary bladder lesions, major vascular
           other than males with primary unilateral IHs.      lesions, urinary retention and testicular problems. 244  Sig-
                                                              nificant advantages for the Lichtenstein repair included a
















































           Evidence in literature                             shorter operating time [TAPP/TEP 65.7 min (40–109) vs
           Systematic reviews and meta-analyses               Lichtenstein 55.5 min (34–99); p = 0.01], a lower inci-
           In meta-analyses from 1999, 2000, 2003 and 2012, TEP  dence of seroma formation (OR 1.42; 95% CI 1.13–1.79;
           and TAPP are compared with all open procedures used for  p = 0.003), and fewer hernia recurrences (OR 2.00; 95%
           IH repair. 199, 202, 242, 243  Only in a 2005 meta-analysis  CI 1.46–2.74; p = 0.00001). 244  The latter was strongly
           subgroup analysis were the TAPP and TEP techniques  influenced by the Veterans Affairs Multicenter Trial, where
           jointly compared with the Lichtenstein operation. 244  This  the minimum mesh size in endoscopic surgery was
           subgroup analysis found significant advantages for the  7.6 9 150 cm. 245  When this study is excluded, there is no



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