Page 43 - International guidelines for groin hernia management
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Hernia

             National registry data analyses usually show a nearly  Of note, mesh polymers themselves do not shrink, but
           linear increase in reoperation rate, reflecting a permanent  the textile itself shortens, pulled together by the contracting
           risk with an almost constant incidence over time. 78, 513, 514  scar. 366  Thick and stiff filaments in a rigid textile implant
           It is therefore, reasonable and logical to think that lifetime  resist shrinkage more than large-pore meshes and offer
           risk of complications will be increased for younger  flexibility adapted to surrounding tissues. 381
           patients, though there are no data confirming this. A long  Mesh shrinkage varies markedly. For plugs, a volume
           implantation period should be considered a mesh-related  reduction due to shrinkage of up to 90% has been reported
                                                                                                   515
           complication risk factor when considering the risk/benefit  with the formation of a so-called meshoma.  It is rea-
           ratio of mesh repair.                              sonable that mesh area shrinkage of greater than 50%
                                                              increases postoperative risks and should be avoided if
           Mesh shrinkage
                                                              possible by minimizing surgical trauma and/or foreign-
           Introduction                                       body reaction. 388, 515–529
           Shrinkage of the mesh—caused mainly by collagen short-  Studies of MRI-visible large-pore PVDF mesh report an
           ening—results in physiological wound contraction. This  up to 20% reduction in mesh surface area indicating a
           phenomenon, in turn, is related to scar tissue amount,  shortening across length and width of about 10%. 530  These
           influenced by surgery-induced local tissue trauma and  studies confirm the results of a 2011 trial performed with
           patient-specific responses to tissue injury.        digital computed radiographs and metal clips at a Licht-
                                                              enstein mesh border. 518
           Key question                                         However, today these changes are small in relation to
                                                              the accuracy of the CT/MRI measurements, and thus need
           KQ10.j Does mesh shrinkage occur, and if so, to what  to be confirmed by further studies.
           extent?




















           Evidence in literature
           It is known that certain patients develop enhanced scar  Chapter 11
           formation and/or marked wound contraction, whereas
           others do not. It is also known that textile meshes induce a
           chronic foreign-body reaction with local inflammation and  Mesh fixation
           fibrosis (see KQ10e). In the case of small-pore meshes this
           reaction can bridge the entire inter-filament distance. 366, 382  R. H. Fortelny, D. L. Sanders and A. Montgomery
           Thus, small-pore meshes develop increased shrinkage in
           the area of surgical trauma. Mesh infection, with its  Introduction
           resultant inflammation and increased fibrosis, exacerbates  Synthetic mesh fixation in both open and laparo-endo-
           this process and results in even more shrinkage.   scopic hernia repair involves a consideration of the strength
                                                              of fixation versus the risk of trauma to local tissues and










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